Graying out and Locking Cells Conditionally

I have a situation where I have 2 questions that I want to ask users of my spreadsheet, the answer is yes or no. I have provided a data validation list box for selection of Yes or No. The default answer for these questions is no.

What I am looking for is a range of Cells G28:I33 to be grayed out and locked to user input when question 1 is No and have a data validation list box and be unlocked to user input if Question 1 is Yes.

The same would apply to Question 2 but I assume the formatting would be the same.

I have attached an example file with desired outcomes and the data validation. In the desired outcome example, I would like the desired outcomes to be there when the cells become active to user input.

Any help would be appreciated

I have gotten the conditional formatting to work but the Data Validation is not this is my formula

=IF($G$25="No", $Q$1,$O$1:$O$2)

Same format but different cells it is not changing the cell contents

What happens is that this statement creates 2 lists a blank list and the Yes/No list, what is does not do is when the parent cell G25 switches from yes to No the original value remains in the cell and does not change to being blank unless manually changed.

I have used conditional formatting for when it says no to make the cell content hidden, and to lock hidden cells when I protect the workbook so they cannot even select the cells when they are grayed out. I think I got it all to work the way I wanted it to.