More efficient way to handle a large number of variables

It's been about 7 years since I've used this forum so please forgive any lapse in decorum.

I have a worksheet with 50+ variables. In each cell of one of the columns, I have a drop-down list with 30+ selections to choose from. Each of those selections has a macro attached to it. Each macro, when run, can change from 1 to 10 of the variables in the worksheet. Each macro will change its assigned variables, then copy a selection from the row above it, paste it into the current row replacing any changed variables with the new variable values.

This is my question: each macro I build has to have all 50+ variables defined in the individual macro. Given that I have to build 30+ macros this seems like a lot of overhead. Is there a way to make the 50+ variables global so that each individual macro only has to define the variables it will be changing?

Thank you for the suggestions, Trevor. I have a more pointed follow-up question.

This how I envision this working: Say a macro runs and changes the values of 5 variables. Then the macro copies the row above and pastes in the current row. Then the macro goes through the current row and replaces the old values of the changed variables with the new values. Now given this order of operations, your array idea seems like the most feasible solution.

I can probably figure out how to make an array of variables and create a for/if loop to replace the new variables but I'm having trouble seeing how this fits in a VBA project. Is the variable array in one module and the macro in a separate module? If so, how do I read the array from the macro module?