Right click on the worksheet's tab, View Code.
Paste the following code:
Option Explicit
Private Sub Worksheet_Change(ByVal Target As Range)
Select Case Target
Case Range("A1")
MsgBox "You changed A1"
Case Range("F3")
MsgBox "You changed F3, and yes this is a different message"
End Select
End Sub
Change cell A1 and you'll get the message, change cell F3 and you'll get the other message. Any other cell does nothing. This code certainly isn't polished or bullet-proof, but it should give you the idea to start with
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