Running three separate macros - on left mouse click, middle wheel click, right mouse click

I have three separate macros and would like to be able to trigger them with three different events - right mouse click, middle wheel click, and left mouse click. Ideally, I'd like to be able to turn this mouse option on and off, with a shortcut keystroke, similar to this:

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And then a shortcut to turn it off. What's the simplest way to do this?

Thank you