locking cells when populated along with a change event

[KK1234]

Hi ,
I have one change event in sheet1 as follows

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I also want to incorporate another change aspect in this so that any cells C2:F2000 and cells I2:I2000, L2:L2000 when populated are locked even if the sheet is unprotected.
Is it possible?
I understand that there can only be one change event per sheet...

Many thanks
Kind regards

[Jakobshavn]

It can all be incorporated into a single sub:

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[KK1234]

Hi
Thanks for quick response.
Id does not work and
Following line gets highlighted ( debug) . I don't understand

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Any help please?
Regatrds

[KK1234]

Bit more clarity.
Column 16 ... when populated deletes row from sheet1 and pastes it in sheet2.

At the same time if any fresh entry is made in columns C:F I want cells to be locked when populated.

Column I and L are with a formula to populate status and a date which depends upon input in column H ( which is independent of everything really)

So the core issue is we are aiming to incorporate locking of cells in C:F when populated ( change scenario) with another one when column 16 is populated.
Hope this may help.
Regards