How to change a substring of a batch of title charts

[pagano8]

Hello, i should like to know if a can replace a substring of a title, but a word given by the user.
I make epidemiological reports, but i just need to change the name of the pathology, the rest of the title leave it as is.
("emergencies january 2013
neumonia women")
just want to change neumonia for hypertension for example. There are graphics for men and women in the same sheet.
I want to ask the user (me) wich word do i want to change and wich word do i am going to change it with.
The examples of code given here change te begining or the end of a title.
Can anybody help me

[Andy Pope]

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[pagano8]

Thank you very much indeed, you have save me a lot of time of work.