Hi,
I think the sample file do not fit exactly the description text - You got there priority 2 - 5 while in description 1 - 3. But let's try, and you can use similar approach modified to meet real needs.
I used the conditional formating rule based on a formula (for cell C1) :
and then copied the formatting (with formats painter) to cells A1:A11 and C1:C11
so the formatting is done only if state is "in progress" and the difference between Updated and Opened is bigger than
4 hrs for priority 1
2 days for priority 2
3, 4 and 20 for priority levels 3-5 resp.
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