I have attached a mocked up version of your worksheet you provided.
I created a new tab called TBL. this is being used for the data validation lists in columns B and C. These are also being used for the vlookups to get the part number.
Column B and C now have a data validation drop down list.
Column D and E have not been touched. Not sure where you get that info from so i assume you manually enter. If need be you can create another drop down list and follow suit.
Column F has the formula:
This is doing a vlookup on column B and C to the table and then concatenating the answers with column D and E. It then adds the 5 digit number starting at 00001 and increasing in value if there are multiples based on a countif formula and a dynamic range.
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