IF then statements and drop downs?

Wondering....can you have col A contain a drop down and then column B include an if then statement that would result in another drop down? IE. Column A has drop down with options of "A", "B", and "C", if the user selects "A", then a drop down would appear in column B containing options "1", "2", and "3". But if the user selects "B" in column A, then a different drop down appears in Column B with options "Yes", "No", and "Maybe"...etc....

Have a look here:

Dependent Lists