HI Xladept,
I have tried, but there is only ("Head, Bi*") selected while the 1st & 2nd character ("BC, HEA*", "Deputy Hea*") not selected. 
I do not expect that filter would be a bit difficult task. If there is no star "*" sign, it works fine. we can use record macro code
This code working fine
With Worksheets("ORIGINATOR")
.AutoFilterMode = False
.Range("A12:TB" & i).AutoFilter Field:=2, Criteria1:="Business Banking"
.Range("A12:TB" & i).AutoFilter Field:=6, Criteria1:=Array("BC, HEAD", "Deputy Head", "Head, Biz Dev"), Operator:=xlFilterValues
End With
but will NOT working for filtering more than 2 items with star "*" sign
With Worksheets("ORIGINATOR")
.AutoFilterMode = False
.Range("A12:TB" & i).AutoFilter Field:=2, Criteria1:="Business Banking"
.Range("A12:TB" & i).AutoFilter Field:=6, Criteria1:=Array("BC, HEA*", "Deputy Hea*", "Head, Bi*"), Operator:=xlFilterValues
End With
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