Using RegEx to parse a string

I'm not quite understanding how to remove characters from a string with RegEx.
I want to remove the "#" sign and the Comma leaving the numeric value in between.

Sample strings:
#1,1d6 5.720 Basic
End result = 1
#21,1e7 5.610
End result = 21
#23.1,1e7 TP_Ø.028_A_B_C
End result = 23.1
#113-J1-1,2c3 TP_.014_J_A^Y
End result = 113-J1-1

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Any assistance is appreciated.

Thank you!
Now back to reading RegEx to see how you structured the pattern.