Why do it manually if the system can do it for you?
Use this modified code to delete rows where (1) the value in column E is duplicated or (2) the value in Column E is blank.
Sub Delete_Multiples()
Dim LastRow As Long
Dim i As Long
LastRow = Cells(Rows.Count, 5).End(xlUp).Row
Application.ScreenUpdating = False
For i = LastRow To 2 Step -1
If Application.WorksheetFunction.CountIf(Range("E:E"), Cells(i, 5)) > 1 Then
Cells(i, 5).EntireRow.Delete
ElseIf Cells(i, 5).Value = "" Then
Cells(i, 5).EntireRow.Delete
End If
Next i
Application.ScreenUpdating = True
End Sub
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