So,

the following works fine for me for the first 2 questions: MultipleOptionButtons_Dis-Enable_Forum_post.xlsm

Check the names of the OP buttons in the name box by right-clicking them, your part is to set the names of all the other OP buttons according to the naming convention in post #2 and assign the "Critically" buttons (1-4 and NA) to the macro "OP_Click()"

If you still have the runtime error I will have a look again, as I said, I need the error number and the line in which the error occurs.