macro to filter all items in Autofilter except 2+ items

I know how i can filter by a list of items in an Auto Filter
AutoFilter Field:=15, Criteria1:= Array("I", "IS"), Operator:=xlFilterValues

And i know how to filter all but 1 item
AutoFilter Field:=10, Criteria1:= "<>I", Operator:=xlFilterValues

but how can i filter out all items in a list besides 2 items ("I","IS")

So the list of options in the autofilter list can vary, but i want to filter by all lines Except "I" and "IS"